The bus depot in Enniskillen offers convenient transportation links to various destinations in both Northern Ireland and the Republic of Ireland. Situated in the heart of the town, it serves as a hub for comprehensive information on all routes connecting to and departing from Enniskillen.

The Ulsterbus service 261, for example, runs approximately every hour, covering the route between Belfast’s Europa bus station and the Enniskillen bus depot, with a travel time of around 2 hours. Additionally, Bus Éireann operates services with direct connections to Dublin, which include Dublin Airport, Cavan, Sligo, and many other locations.